ECE WEB

Ph.D., Bioengineering, University of Pennsylvania, 1992
M.S., Biomedical Engineering, Chinese Academy of Medical Science, 1987
B.S., Applied Mathematics, Northern Jiaotong University, 1983

Recent Publications

Awards and Honors

Aguirre A, Puyun Guo, P, Gamelin J, Yan S, Sanders M, Brewer M, Zhu Q., "Co-registered 3-D ultrasound and photoacoustic imaging system for ovarian tissue characterization,", Journal of Biomedical Optics. Accepted.

Ardeshirpour A., Huang MM, and Zhu Q., "Effect of the chest wall on breast lesion reconstruction,", Journal of Biomedical Optics. Journal of Biomedical Optics, July/August 2009

John Gamelin, Anastasios Maurudis, Andres Aguirre, Fei Huang, Puyun Guo, Lihong V. Wang, and Quing Zhu, "A real-time photoacoustic tomography system for small animals,", 22 June 2009 Vol. 17, No. 13 OPTICS EXPRESS 10489

Gamelin J., Yang, Y., Biswal N., Chen, Y., Yan S., Zhang X., Karemeddini M., Brewer M., and Zhu Q., "A prototype hybrid intraoperative probe for ovarian cancer detection,", Optics Express Vol. 17, Iss. 9, pp. 7245-7258 (2009)

Xu C, Das M, Ardeshirpour Y, Zhu Q, "An image reconstruction method for a two-layer tissue structure accounts for chest-wall effects in breast imaging," Journal of Biomedical Optics, in Press.

Yuan BY, Gamelin J and Zhu Q, "Mechanisms of the ultrasonic modulation of fluorescence in turbid media," Journal of the Optical Society of American A. J. Opt. Soc. Am, in Press.

Zhu, Q, Tannenbaum S, Hegde, P, Kane M, Xu C, Kurtzman SH, "Noninvasive monitoring of breast cancer during neoadjuvant chemotherapy using optical tomography with ultrasound localization," Neoplasia, Feature Article, Oct Vol. 10 Iss. 10, 2008

Xu C., Yuan B, Zhu Q, "An optimal probe design for breast imaging using near infrared diffused light," Journal of Biomedical Optics, 13(4), 044002-1:10, July/August 2008

Jiang Z, Zhu Q., Piao, DQ, "Minimization of geometric-beam-broadening in a grating based time-domain delay line for optical coherence tomography application," Journal of the Optical Society of American A. J. Opt. Soc. Am A 24(12):3808:3818 2008

Gamelin J, Aguirre A, Maurudis A, Huang F, Castillo D, Wang, VL, and Zhu Q, "Curved array photoacoustic tomographic system for small animal imaging," Journal of Biomedical Optics 13(2), 024007 1:10, March/April 2008

Chen Y., Willett P., Zhu Q., "Frequency tracking in optical Doppler tomography using an adaptive notch filter," Journal of Biomedical Optics, Jan/Feb issue, 2007.

Zhu Q., Xu C., Guo P., Aguirre, A., Yuan, BY., Huang F., Castilo D., Gamelin J. , Tannenbaum S., Kane M., Hegde P., Kurtzman, S., "Optimal probing of optical contrast of breast lesions of different size located at different depths by US localization, Technology in Cancer Research and Treatment," August, 2006.

Yuan B, Zhu, Q.," Separately reconstructing the structural and functional parameters of a fluorescent inclusion embedded in a turbid medium," Optics Express, July, 2006.

Das M., Xu C., Zhu Q., "Analytical solution for light propagation in a two-layer tissue structure with a tilted interface for breast imaging," Applied Optics, July 10, 2006.

Zhu, Q., Cronin, E., Currier, A., Vine, HS, Huang, MM, Chen, NG, Xu, C., "Benign versus Malignant Breast Masses: Optical Differentiation using US to Guide Optical Imaging Reconstruction," Radiology, Oct, 57:66, 2005.

Zhu Q., "Optical tomography with ultrasound localization: initial clinical results and technical challenges," Technology in Cancer Research & Treatment, 4(3): 235-244, 2005.

Zhu, Q, Kurtzman, S, Hegde, P., Tannenbaum S, Kane, M, Huang, MM, Chen, NG, Jagjivan B, Zarfos, K, "Utilizing optical tomography with ultrasound localization to image heterogeneous hemoglobin distribution in large breast cancers," Neoplasia, 7(3) 263-270, 2005.

Xu, C, Zhu, Q., "Estimation of chest wall induced diffused wave distortion with the assistance of ultrasound," Applied Optics, July 10, 2005.

Chen, Y, Otis, L, Piao, DQ, Zhu, Q., "Characterization of dentin, enamel and carious lesions by a polarization-sensitive optical coherence tomography system," Applied Optics, April 44(11): 2041-2048, 2005.

Piao, DQ, Sadeghi, MM, Zhang, JS Chen, Y., Sinusas, AJ, Zhu, Q., "A hybrid positron detection and optical coherence tomography system: Design, calibration and experimental validation with rabbit atherosclerotic models," Journal of Biomedical Optics, July/August Issue 2005.

Piao, DQ, Zhu, Q., "Direct Bi-directional Angle-insensitive Imaging of the Flow Signal Intensity in Doppler Optical Coherence Tomography," Applied Optics, 44(3) 348-357, 2005.

Huo, Y, Bansal, R, Zhu, Q., "Modeling of noninvasive microwave characterization of breast tumors," IEEE Transactions on Biomedical Engineering, 51(7), 1089-1094, 2004.

Otis, L, Piao, DQ, Gibson, C, Zhu, Q, "Quantifying labial blood flow using optical Doppler tomography," Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 98( 2 ), 189-194, 2004.

Yuan, BY, Chen, NG and Zhu, Q., "Emission and absorption properties of indocyanine green in intralipid solution," Journal of Biomedical Optics, May/June issue,497-503, 2004.

Chen, NG, Huang, MM, Xia, HJ, Piao, DQ, Cronin, E, Zhu, Q., "Potable near infrared diffusive light imager for breast cancer detection," Journal of Biomedical Optics, MAY/JUNE ISSUE, 504-510, 2004.

Piao DQ and Zhu, Q., "Power-efficient grating-based scanning optical delay line: time-domain configuration," Electronics Letters, 40(2), 97-98, 2004.

Yan, SK, Piao, DQ, Chen Y, Zhu, Q, "A DSP-based real-time optical Doppler tomography system," Journal of Biomedical Optics, May/June issue, 454-463, 2004.

Chen, NG and Zhu, Q., "Time-resolved diffusive optical imaging using pseudo-random bit sequences," Optics Express, 11(25), 3445-3454, 2004.

Huang, MM and Zhu, Q., "A Dual-mesh optical tomography reconstruction method with depth correction using a priori ultrasound information," Applied Optics, Vol. 43, No.8, 1654-1662, 2004.

Zhu, Q., Huang, MM, Chen, NG, Zarfos, K, Jagjivan, B, Kane, M, Hedge P., Kurtzman, SH, "Ultrasound-guided optical tomographic imaging of malignant and benign breast lesions: initial clinical results of 19 cases," Neoplasia, 5(5), 379-388, 2003.

Zhu, Q, Piao, DQ, Sadeghi, M, Sinusas, A, "Simultaneous optical coherence tomography imaging and beta particle detection," Optics Letters, Sept 15 issue, 2003.

Piao DQ and Zhu, Q., "Quantitation of Doppler angle and Flow Velocity mapping by Combining Doppler Shift and Doppler Bandwidth Measurements in Optical Doppler Tomography," Applied Optics, Sept issue, 2003.

Huang, MM, Xie, TQ, Chen, NG, and Zhu, Q, "Simultaneous reconstruction of absorption and scattering maps with ultrasound localization: feasibility study using transmission geometry," Applied Optics, Vol 42 (19): 4102-4114,2003.

Piao, DQ, Otis, L., and Zhu, Q., "Doppler angle and Flow Velocity mapping by Combining Doppler Shift and Doppler Bandwidth Measurements in Optical Doppler Tomography," Optics Letters, Vol 28 (13): 1120-1122, 2003.

Zhu, Q., Chen, NG and Kurtzman, S.,"Imaging tumor angiogenesis using combined near infrared diffusive light and ultrasound" Optics Letters, 28(5) 337-339, 2003.

Awards and Honors

The Connecticut Technology Council 2007 Women of Innovation Award
Member of Connecticut Academy of Science
Associate editor of IEEE Trans. of systems, Man and Cybernetics
Recipient of Career Development Award of DOD ARMY Medical Research and Materiel Command of Breast Cancer Program (9/94-8/1/98, DAMD17-94-J-4133)
Senior Member of IEEE BME Society

U.S. Patent 6,813,050, "Rotary Mirror Array for Fast Optical Tomography", by Chen, N.G and Zhu, Q., 2004.
U.S. Patent 6,264,610, "A Novel Hybrid Imaging Transducer Using Ultrasound and NIR Light", by Zhu, Q., 2001.
U.S. Patent 5,935,068, "System and Method for Improving Ultrasound Imaging Contrast by Amplitude Compression of Ultrasonic Wavefront Signals", by Zhu, Q. and Steinberg, B., 1997.

IEEE Ultrasonics, Ferroelectrics & Frequency Control, IEEE Medicine and Biology, American Institute of Ultrasound in Medicine, SPIE Optical Society and Optical Society of American